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Thabor Tx
Start-up
6 employees
Immunology - Biology
CDI
Rennes, France
40k€ - 50k€
June 22, 2022

SCIENTIST LEVEL II

Company description

Thabor Therapeutics, an emerging biotechnology company focused on developing first-in-class monoclonal antibodies to treat chronic inflammatory diseases, more particularly Inflammatory Bowel Diseases.

Job description

Thabor Therapeutics, an emerging biotechnology company focused on developing first-in-class monoclonal antibodies to treat chronic inflammatory diseases, more particularly Inflammatory Bowel Diseases.

We are recruiting a scientist level II responsible for drug development. You will design and conduct experiments to validate drug candidates. You will supervise external research activities with CROs/CDMOs. Your objectives will be determined by the R&D Director you will report to.

 

The position is based in Rennes with occasional travels to Paris. 

Your responsibilities will include:

-          Planning and conducting experiments

-          Recording and analyzing data

-          Carrying out fieldwork, eg collecting samples

-          Developing, Optimizing, Validating and transfer assays for drug selection

-          Presenting results to senior/other research staff

-          Writing reports

-          Preparing data for research proposals and funding applications/bids

-          Organizing product/materials testing

-          Ensuring traceability (eNoteBook) and that quality standards are met (GXPs)

-          Collaborating/Liaising with research and/or production staff, academic partners

-          Developing original solutions to problems

-          Keeping up to date with relevant scientific and technical developments

-          Writing SOPs

-          Liaising with CROs / CDMOs

-          Ensuring proper care in the use and maintenance of equipment and supplies; promoting continuous improvement of workplace safety and environmental practices

-          Ordering lab supplies, managing stocks

-          Performing miscellaneous job-related duties as assigned

 

Desired profile

Qualifications and training required

-          Ideally 2 years in a biotech/pharmaceutical environment, or 2-4 years of Post-doc position in the related discipline (mAb development with sound experience in immunotherapy).  A plus would be a knowledge in inflammatory diseases.

-          English (oral and written) is mandatory

-          Excellent hands-on knowledge in Cell preparation, (Ficoll, sorting, Freeze/Thaw etc.)

-          Flow cytometry (analyzers, sorters); ELISAs; IHC ; cytokine multiplex; ADCC; Receptor internalization 

-          Bioassays (chemotaxis; cell proliferation; NADA; cell differentiation; organoids)

-          Mastering molecular and cell biology (cell culture, protein analysis)

-          You have already carried out recombinant protein synthesis (design, manufacturing, vector, expression, and purification)

-          Mastering current analytical techniques for the characterization of proteins and/or antibodies and protein/antibody coupling/conjugation

-          Experienced in project management

-          Management of technicians and engineers

-          Ability to manage highly complex projects

-          Flexibility

-          A logical and independent mind

-          Meticulous attention to details

-          Excellent analytical skills

-          Good Teamworking abilities and Communication skills

-          Decisiveness

-          Autonomy

Education
-         At least a PhD in immunology or cell biology is required 

Working Conditions and Physical Effort
-          No or very limited physical effort required

-          Work is normally performed in a typical interior/office and laboratory work environment

-          Work environment involves some exposure to biohazards or chemical risks, which require following safety precautions