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200 employees
Evry-Courcouronnes, France (91)
Aligned with INSERM (about 2621 euros monthly gross salary, adapted to professional experience on equivalent positions)
January 28, 2022

Postdoctoral position in gene therapy for inherited inflammatory and immune disorders

Job description

The Immunology and biotherapies (IMBI) group in the INTEGRARE unit ("integrated genetic approaches for the treatment of rare genetic diseases", UMR_S951) at Genethon focuses on gene therapy and the immune system. The two main research interests in this group are: the development of new gene therapies based on genetically modified immune or blood cells; and the development of immunologically well-tolerated strategies and vectors. The group is directed by Dr. A. Galy with adjunct direction from Dr. Céline Rocca.

IMBI is seeking a junior post-doctoral fellow to conduct a new therapeutic project for an inherited disorder of inflammation. The approach will be based on gene editing and ultimately, aims to deliver all the components within target cells in vivo. The candidate will work in state-of-the art facilities, will have access to patient cells and will have the possibility to utilize a humanized mouse model, already in place in the laboratory, to demonstrate the efficiency of the approach. Under the supervision of Dr. Céline Rocca, the candidate will be responsible for designing, developing and implementing experimental protocols. The candidate is expected to publish and to present research results at scientific meetings.

Fixed-term contract of 2 years, starting no later than October 1st, 2022.

Desired profile

-  PhD in molecular or cell biology, physiology or other relevant life sciences obtained in 2019, 2020 or 2021

-  Experience in molecular and cellular biology techniques

-  Experience in gene therapy, gene editing will be a plus

-  Experience working with mice will be a plus

-  Ability to conduct a project independently and work with other members of the team

-  Excellent organizational skills, rigor and reliability

-  English language : B2 à C2 (CERL)

-  Good oral, written and presentation skills